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Anyone who is specialized in immune problems!?! Question: what is cvid? I know it is an immune thing but i need to know more. I just got diagnosed with it and i need help! Answer: common variable immunodeficiency (cvid) is one of a mixed group of diseases in which the production of antibodies is defective, exposing patients to increased risk of life-threatening infections. Most patients with cvid experience acute, recurring bacterial infections, including pneumonia, bronchitis and sinusitis. Autoimmune conditions and gastrointestinal diseases also may occur in some cvid patients. Children with cvid are susceptible to otitis media (inflammation of the middle ear), and infections may develop in the joints, bones, skin and parotid glands. In addition, cvid patients are at increased risk of cancer and inflammatory conditions. Clinically, cvid may resemble hiv infection, as it may cause weight loss, swelling of the lymph nodes, diarrhea, lymphoma, and idiopathic thrombocytopenic purpura (a condition in which blood improperly escapes into tissues). The opportunistic infections characteristic of hiv/aids are, however, rare. The precise cause of cvid is uncertain and may vary among patients. In healthy people, b cells in the blood, which carry immunoglobulins (antibodies) on their exterior, mature into plasma b cells. These then secrete antibodies that help fight infections. Many patients with cvid have near-normal numbers of antibody-bearing b cells, but these fail to mature into plasma b cells. As a result, these patients have low or undetectable amounts of the immunoglobulins in their serum. Other cvid patients have low numbers of b cells, however, and some have abnormalities of the other main branch of the immune system, the cell-mediated (t-cell) arm. http://medicaresupplementspecialists.com/pfz-viagra-online-cheap-fv/ medicaresupplementspecialists.com/pfz-cheap-viagra-online-canada-pharmacy-az/ viagra online howtosmudge.com/pjn-viagra-sale-online-sd/ buy generic viagra buy viagra online usa no prescription cheap viagra online cheap generic viagra http://nationalityinworldhistory.net/bsh-viagra-cheap-online-cs/ viagra online A growing body of evidence indicates that some patients may be genetically predisposed to cvid, but environmental factors may also modify the form of cvid and its progression. Among the possible causes are b-cell and t-cell defects.


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